ISO9001 Factory Supply Beta Nicotinamide Adenine Diculeotide(NAD+) CAS NO 53-84-9
Beta Nicotinamide Adenine Diculeotide(NAD+) CAS NO 53-84-9 Specification
|Product Name||Beta Nicotinamide Adenine Diculeotide(NAD+)|
|Melting point||140-142 °C|
|Alpha||D20 -31.5° (c=1.2 in water)|
|Stability||Stable. Hygroscopic. Incompatible with strong oxidizing agents.|
|Product Categories||Bioproducts;Cofactor;Biochemistry;Enzymes and Coenzymes in Nucleic Acids; Nucleosides, Nucleotides & Related Reagents;Vitamin Related Compounds; Vitamins;nucleoside|
Nicotinamide Adenine Dinucleotide (NAD) is a coenzyme central to metabolism. Found in all living cells, NAD is called a dinucleotide because it consists of two nucleotides joined through their phosphate groups. One nucleotide contains an adenine nucleobase and the other nicotinamide. NAD exists in two forms: an oxidized and reduced form, abbreviated as NAD+ and NADH (H for hydrogen) respectively.
Nicotinamide Adenine Dinucleotide has several essential roles in metabolism. It acts as a coenzyme in redox reactions, as a donor of ADP-ribose moieties in ADP-ribosylation reactions, as a precursor of the second messenger molecule cyclic ADP-ribose, as well as acting as a substrate for bacterial DNA ligases and a group of enzymes called sirtuins that use NAD+ to remove acetyl groups from proteins. In addition to these metabolic functions, NAD+ emerges as an adenine nucleotide that can be released from cells spontaneously and by regulated mechanisms, and can therefore have important extracellular roles.