Hexadecanamide,Palmitoylethanolamide ,PEA,629 54 9 (60761417732)

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Product Overview

Description

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Hexadecanamide [629-54-9]

 

Name

Hexadecanamide

Synonyms

Palmitamide; Amide Hpl; Cetyl Amide

Molecular Formula

C16H33NO

Molecular Weight

255.44

CAS Registry Number

629-54-9

EINECS

211-095-5

SMILES

C(CCCCCCCCCC)CCCCC(N)=O

InChI

1S/C16H33NO/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16(17)18/h2-15H2,1H3,(H2,17,18)

InChIKey

HSEMFIZWXHQJAE-UHFFFAOYSA-N

 

Desity

0.87g/cm3 (Cal.)  ref.

Melting point

106°C (Expl.)  ref.

Boiling point

392.377°C at 760 mmHg (Cal.)  ref.

Flash point

191.103°C (Cal.)  ref.

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Description

Palmitoylethanolamide (PEA) is an endogenous fatty acid amide, belonging to the class of nuclear factor agonists. PEA has been demonstrated to bind to a receptor in the cell-nucleus (a nuclear receptor) and exerts a great variety of biological functions related to chronic pain and inflammation. The main target is thought to be the peroxisome proliferator-activated receptor alpha (PPAR-α).PEA also has affinity to -like G-coupled receptors GPR55 and GPR119. PEA cannot strictly be considered a classic endo because it lacks affinity for the receptors CB1 and CB2. However, the presence of PEA (and other structurally related N-acylethanolamines) has been known to enhance anandamide activity by an "entourage effect".

Application

Palmitoylethanolamide/PEA has been shown to have anti-inflammatory, anti-nociceptive, neuroprotective, and anticonvulsant properties.

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60761417732
0.0339 s.