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Human vaccine Veterinary vaccine Bioreactor Fermenter Fermentor
Introduction
Rotech has been engaged in the research, development, design and manufacture of bioreactors for more than 20 years.which is engaged in R&D, design, manufacturing, installation, commissioning and technical services of various microorganisms, plant cells and animal cell reactors (fermenters); providing customers with turnkey projects like fermentative biological projects that meet GMP requirements.
Application: human vaccines, veterinary vaccines, monoclonal antibodies, recombinant proteins, cell therapy, new drug development and production, etc.
Fermenters/Reactor specifications: 5L----6000L.
Main description
Stainless steel fermentation tank use for test project of yeast, enzymes, microorganisms such as fungi and bacteria culture test.it is made by stainless steel. equipment exquisite, beautiful imported equipment can be rivaled.
Three major components including tank, piping and control system.
Tank is SUS316L stainless,jacket is made by SUS304. Stainless steel polished precision Ra≤0.4 inside, Ra≤0.6 outside, equipment design, manufacture in accordance with GMP standards.
Technical parameters
Nominal volume
| 10/20/30/50/80/100/200L/500L/1000L /5000L |
Diameter to height ratio | C |
Liquid filling factor | 70% |
Tank body description | The main body is made of all stainless steel 316L tank body and jacket, with no dead corners in the tank; with special sampling for fermentation tank, discharge valve, and transfer pipeline. Adopting a wide viewing angle of the tank liquid level observation mirror, safety light, with temperature, PH, DO, defoaming, liquid level interface, injection port, refilling port, and multiple spare ports, all welds are firm, neat and beautiful |
Mixing method | Magnetic stirring or mechanical stirring one of the two optional |
Sterilization method | On-site sterilization auto control or manual control |
Control system | Siemens PLC, industrial LCD touch computer control, parameters can be set to store, can be remotely connected to the computer through the USB interface, |
Mechanical sealing system | High-powered stirring oar, anti-foam oar; AC electrical machine: infinite speed variation; rpm in the fermenter: 50~1000 rpm±1%, The height of the stirring oar can be adjusted |
Temperature detection and control | Heat by thermostatic water tank and circulate by circulating pump (Grundfos, Denmark), auto control (cooling water+5℃) to 65℃±0.1℃, temperature probe (PT100) |
pH detection and control | 2.00-12.00±0.05 pH, auto control by adding acid and base, pH sensor (Mettler/Hamilton, Switzerland) and shielding lead (Mettler/Hamilton, Switzerland). fermenter is auto controlled with peristaltic pump |
| DO detection and control | 0-150±3% displaying precision 0.1%, sensor (Mettler/Hamilton, Switzerland) and shielding lead (Mettler/Hamilton, Switzerland) |
| Feed control | Uses peristaltic pump (Spirax, UK) to add materials |
| Anti-foam control | Tested by sensor and added anti foamer by peristaltic pump Intake control (air) manual control rotameter |
| Pressure detection and control | Pressure Control: Pressure meter and digital display and digital remote control, pressure control we are compliant fermentation equipment for research, development, pilot and production applications |
| Optional function | |
| A: Tank weighing | |
| B: Weighing with replenishing balance | |
| C: Automatic control of air flow | |
| D: Online detection and control of methyl alcohol content | |
| E: Bypass pure oxygen | |
| F: Online detection of redox potential | |
| G: Tank pressure detection | |
| H: Online detection of O2 and CO2 content in tail gas | |
| I: Automatic tank cleaning function | |
| J: Automatic sterilization function | |
| K: Tank cover automatic lifting function | |








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