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Technical Parameters | ||||
Ultra high pressure liquid chromatograph | Pump system | dual-cylinder HPG (high-pressure mixing) dual-channel | ||
Flow range | 0.001 ~ 2.000mL/min (maximum 5 mL/min) | |||
Flow accuracy | 1% or 10uL/min ≤0.075% RSD or 0.005min SD | |||
Maximum work pressure | 0 ~ 18850psi (0 ~ 1300 bar) | |||
Sample capacity | 108 positions (2ml vial) | |||
Sample temperature | 4 ~ 40℃ | |||
Triple Quadrupole Mass Spectrometer | Ion source | 1. Ion source ensures that number of ionization is maximized, also neutral particles and high-energy ion clusters that generate noise are minimized. | ||
2. Axial direction of spray atomizer is perpendicular to interface of orifice plate to improve spray effect and greatly reduce entry of neutral particles into mass spectrometer, thereby eliminating noise. | ||||
3. By providing Electrospray Ionization (ESI) source and atmospheric pressure chemical ionization source (APCI), substances of different polarities can be analyzed. | ||||
Ion guide | High frequency (RF) double ion funnel is optically optimized to transport a wide range of ions while performing efficient ion focusing. | |||
Quadrupole and front and rear filters 1 and 2 are used to optimize ion transmission and spectral level resolution. | ||||
Collision unit | Collision unit has optimized mode of high-pressure 180-degree bending, and at same time eliminates interference. | |||
Detector | Electron accelerator with acceleration after 5kV. | |||
Vacuum system | Two single-stage 40L/h primary pumps Three-stage 25/300/400L/s turbomolecular pumps | |||
System performance | 1. MRM sensitivity, signal-to-noise ratio (S/N), ESI positive ion 1pg reserpine, scan m/z 609 to 195 for quantification. S/N: 1000000:1 | |||
2. MRM sensitivity, signal-to-noise ratio (S/N), ESI negative ion 1pg chloramphenicol, scan m/z321 to 152 for quantification. S/N: 500000:1 | ||||
3. Mass range: m/z 10 ~ 1250 | ||||
4. Polarity switching: 25ms | ||||
5. Mass resolution: 0.7 Da to 4.0 Da (user adjustable) | ||||
6. Quality stability: 0.1Da/24h | ||||
7. Dynamic range: >105 | ||||
8. Scan mode: full scan, product ion scan, precursor ion scan, neutral loss scan, selective ion scan (SRM/MRM) | ||||
9. Maximum scanning rate: 20000 Da/S | ||||
10. Maximum MRM collection rate: 600 MRMs/S | ||||
11. Minimum MRM residence time: 1.0 ms | ||||




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