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PDRN (PolyDeoxyRiboNucleotide) from Salmon DNA:



Sponge microneedles are minute structures derived from freshwater sponges and aquatic organisms. Evolved naturally to thrive in their environment, these biological needles are imperceptibly small, often found in powder or gel form. Functionally akin to tiny needles, they can delicately penetrate skin pores, earning them the nickname "sponge bone needles." Extracted from freshwater sponges' delicate, spongy spicules, they find wide application in acne treatment and skincare routines.
Advantages
It can open skin channels directly to the dermis, help activate skin microcirculation, relieve clogged skin pores, accelerate skin metabolism, accelerate the natural exfoliation of aging stratum corneum, and shorten the skin renewal cycle from 28 days to 1 week. Compared with roller microneedles, this needle has more and smaller needles and can cover more skin pores.










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