Rapamycin,Sirolimus CAS 53123 88 9

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Product Overview

Description

 

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Identification

 

NameRapamycin,Sirolimus
Structure    Sirolimus.png
Other name

Rapamycin; Sirolimus;

53123-88-9; (-)-Rapamycin; Rapamycin (Sirolimus)

CAS NO.53123-88-9
Molecular FormulaC51H79NO13
Molecular Weight914.187 g/mol

  

Chemical and Physical Properties
AppearanceWhite to off-white crystalline powder
SolubilitySol in ether, chloroform, acetone, methanol, and DMF; very sparingly sol in hexane and petr ether.
Melting point183-185 deg C
Quality standard In-house standard,Assay Calculates anhydrous C51H79NO13 ≥95.5%

 

Application
Drug IndicationSirolimus, also known as rapamycin, is a macrolide compound that is used to coat coronary stents, prevent organ transplant rejection and to treat a rare lung disease called lymphangioleiomyomatosis. It has immunosuppressant functions in humans and is especially useful in preventing the rejection of kidney transplants. It inhibits activation of T cells and B cells by reducing the production of interleukin-2 (IL-2).
Categories

Transplant Agents,

Immune Suppressant,

Anti-Bacterial Agents

Antifungal Agents,

Antibiotics,

Antineoplastic (Anti-cancer)

Handling and storage
Safety and HazardsNone hazards.
Handling and storageStore at room temperature below 30 deg C (86 deg F).
Sample packageAluminium foil bag
Commercial package25kg Fiber drum
UN Code Not classfied
HS Code2941909090
Shipping groupShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Sales restrictionNO
OriginChina

 

Technical Support
Sirolimus (Rapamycin)  STD Data sheetYes
Sirolimus (Rapamycin)  MSDSYes
Sirolimus (Rapamycin)  COAYes
Sirolimus (Rapamycin)  HPLCYes
Sirolimus (Rapamycin) Transport certificateYes

 

Supply ability
Monthly capacityMore than 10kgs
GMP& DMFAvaiable,yes

 

Related APIs
Related APIS

Fingolimod;
Methotrexate;
Lenalidomide;
Everolimus;
Tacrolimus
Tofacitinib ;
paclitaxel;
Ciclosporin A

 

 

 

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0.1889 s.