Betaine, CAS : 107 43 7,for biology research

Product Overview

Description

Betaine

Detailed Product Description

Synonym	oxyneurine, glycine betaine, (carboxymethyl)trimethylammonium inner salt, 1-carboxy-N,N,N-trimethylmethanammonium inner salt
Molecular Formula	C5H11N+O2
Molecular Weight	117.15
CAS Number	107-43-7

 

Betaine is a reagent that is used in soldering, resin curing fluxes, and organic synthesis. Betaine compounds occur naturally in plants and animals, such as in sugar beets and marine algae. A review of the role of glycine betaine in protecting plants from environmental stress has been published. The role of betaine and other organic osmolytes in maintaining osmolarity in mammalian cells has been reviewed. Betaine has been reported to diminish the base pair composition dependence of DNA thermal melting transitions, with a concentration of 5.2 M betaine being the value at which AT and GC base pairs are equally stable. Betaine has subsequently found application in the polymerase chain reaction (PCR). The usefulness of betaine in PCR has resulted from its ability to enhance DNA amplification by diminishing the formation of secondary structure in GC-rich DNA regions. A protocol for the production of long-chain cDNAs that uses betaine and trehalose has been published.

The permanent positive charge on betaine makes it a target of study for mass spectrometry (MS) analysis by such methods as electrospray ionization (ESI) MS. A protocol for the analysis of betaine and other choline related compounds from tissues that combines HPLC with isotope dilution ESI-MS has been described.