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Gamma-poly-glutamic acid (gamma-PGA) is a natural occurring, multi-functional, and biodegradable
biopolymer. It is produced through fermentation by Bacillus subtilis using glutamic acid. PGA is consists of glutamic acid monomers crosslinked between α-amino and γ-carboxyl groups, and the molecular weight of PGA is usually between 5kDa to 2000kDa, It is water-soluble, edible and non-toxictowards human, and is environment friendly. It has broad applications in the fields of medicine, food, cosmetics, and water treatment.
Gamma-PGA
Other Name: Natto Gum; PGA;γ-PGA;γ-Polyglutamic Acid; Gamma-Polyglutamic acid Molecular Structure: CAS No.:25513-46-6 Appearance: White free-flow powders Molecular Wt : from 5kDa to 2000kDa
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The COA of Gamma-PGA
Test Items | Specification |
Appearance | White to off white granular or powder, no Agglomeration |
Assay(HPLC) | ≥90% PGA-Na |
Loss on drying(105℃, 2h) | ≤8% |
Molecular wt(Da) | ≥2,000,000 |
Visosity 1% (60rpm) | ≥90mPa.s(cP) |
Heavy metals(Pb) | ≤20mg/kg |
pH value(10g/L, 25℃) | 6.3-7.3 |
Total plate count(CFU/g) | ≤100 |
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Multi-effects
Being the cosmetic-grade ingredient, γ-PGA has an extensive distribution of molecular weight. Different molecular weights of γ-PGA contribute to 14 skin care effects of γ-PGA . Molecular weight of 200,000-350,000D functions in stimulating cell growth and tightening skin, 1150,000-1350,000D inhibiting TYR activity for better whitening effect, 1150,000-1450,000D increasing hydrating effect and reducing TEWL.
Dual moisturizing
Being the natural fermented ingredient for beautiful skin, γ-PGA form a protective film on skin surface to defense moisture loss and UV rays, but also to reduce the growth of bacteria and make your skin smooth. γ-PGA, fresh and not greasy, do not plug the pores, is different from the ordinary skin care products.
Being a unique component to promote NMF growing, γ-PGA deeply infiltrates into the horny layer of skin and moisturizes the skin to take skin brightening to new height. γ-PGA is not a moisturizer of self-repair in skin care products.
Efficient
γ-PGA well solve the problems of water shortage, dryness and wrinkles of skin caused by environmental pollution. It is far better than hyaluronic acid and collagen.

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