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High Efficiency Mixing Granulator
Usage
High shear mixer granulator is used in pharmaceutical solid dosage area for mixing and granulation application. It's the major processing equipment in solid dosage production line. The equipment is PLC automation controlled and well satisfies the current GMP and Pharmacy Code regulation.
Working Principle
The raw material is loaded into the container via self vent vacuum sys(in case this option selected), or other loading sys as requested; and mechanically fluidized inside the container under the impeller force, which realizes the perfect mixing performance. Loading the binder into the container and starts the chopper. The material coheres together by the binder which forms the binder bridge for form the core granules. Under the mechanical energy conversion, the qualified granule grows up and formed.
Features
1. Cylinder & conical material container structure, Z shaped mixing impeller, together forms the perfect mixing and granulation performance with qualified wet granules.
2. Modular designed platform and on-line wet cone mill option satisfies with various process and facility conditions. 3. Pressured spray, manual or other requested binder loading sys option satisfies with various product & granulation requests.
4. Designed with granulation end-point detection function, satisfies with the process reproducibility request.
5. Designed with self-vent vacuum loading sys for raw material, reduce the labor and avoids dust and cross contamination, satisfies with the current GMP clean production request.
6. Compound mechanical & air sealing structure avoid any material leakage and cross contamination, satisfies with the current GMP clean production request.
7. Variable impeller & chopper speed controlled by VFD and setup from HMI, satisfies with various product mixing & granulation requests.
Technical Data
| Model | 10 | 25 | 50 | 100 | 150 | 200 | 300 | 400 | 500 | 600 | 800 | 1000 | 1200 |
| Container volume(L) | 10 | 25 | 50 | 100 | 150 | 200 | 300 | 400 | 500 | 600 | 800 | 1000 | 1200 |
| Working volume(L) | 4-8 | 10-20 | 20-40 | 40-80 | 60-120 | 80-160 | 100-240 | 160-320 | 200-400 | 240-480 | 320-640 | 400-800 | 480-960 |
| mixing power (KW) | 1.1 | 2.2 | 5.5 | 11 | 15 | 18.5 | 22 | 30 | 37 | 45 | 55 | 55 | 75 |
| Mixing speed (rpm) | 10-600 | 5-420 | 5-355 | 5-287 | 5-240 | 5-223 | 5-200 | 5-185 | 3-172 | 3-162 | 3-148 | 3-140 | 3-133 |
| chopper power | 0.75 | 1.1 | 1.5 | 3 | 3 | 4 | 5.5 | 5.5 | 7.5 | 7.5 | 11 | 15 | 15 |
| choppr rpm | 1000-2800 | 1000-2800 | 1000-2800 | 1000-2800 | 1000-2500 | 1000-2500 | 1000-2500 | 1000-2500 | 1000-2500 | 1000-2500 | 1000-2000 | 1000-1500 | 1000-1500 |
| wet mill power (KW) | -- | 0.75 | 0.75 | 0.75 | 1.5 | 3 | 3 | 3 | 4 | 4 | 4 | 5.5 | 5.5 |
| mill rpm | -- | 300-1400 | 300-1400 | 300-1400 | 300-1400 | 300-960 | 300-960 | 300-960 | 300-960 | 300-960 | 300-960 | 300-1400 | 300-1400 |
Compressed air consumption m3/min | 0.03 | 0.05 | 0.05 | 0.1 | 0.1 | 0.2 | 0.2 | 0.2 | 0.3 | 0.3 | 0.3 | 0.3 | 0.3 |


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