High Grade Calcium Hydroxyapatite Powder with Good Price

Hydroxylapatite is commonly used as a filler to replace amputated bone or as a coating to promote bone ingrowth into prosthetic implants. Although many other phases exist with similar or even identical chemical makeup, the body responds to them very differently. Coral skeletons can be transformed into hydroxylapatite by high temperatures; their porous structure allows relatively rapid ingrowth at the expense of initial mechanical strength. The high temperature also burns away any organic molecules such as proteins, preventing an immune response and rejection.

Many modern implants, e.g. hip replacements, dental implants and bone conduction implants, are coated with hydroxylapatite. It has been suggested that this may promote osseointegration.[citation needed] Porous hydroxylapatite implants are used for local drug delivery in bone. It is also being used to repair early lesions in tooth enamel.

In spite of attractive biological properties, hydroxylapatite, and materials based thereon, have some drawbacks, such as low bioresorption rate in vivo, poor stimulating effect on the growth of new bone tissues, low crack resistance and small fatigue durability in the physiological environment. The application of modified hydroxylapatite opens up the opportunities for the preparation of artificial bone substances for implants and a large variety of drugs for curing different lesions of bone, soft and mucous tissues of the individual. A promising method of modification is the introduction of fluorine or silicon into the primary structure with the formation of fluorine- or silicon-substituted hydroxylapatite. The introduction of fluorine increases the resistance to biodegradation[18] and improves the adsorption of proteins and adhesion of the coating to the metal substrate.