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Introduction
Isotretinoin
CAS: 4759-48-2
Molecular Weight:300.44
Molecular Formula:C20H28O2
Standard:USP26/28,EP5
Assay:98.0-102.0%
Description:yellow crystalline powder.
Use: Solvent for cutis cutin
Appearance: Yellow or orange crystalline or crystal powder, insoluble in water, slightly soluble in ethanol, very slightly soluble in ether, soluble in chloroform.
Isotretinoin (13-cis-Retinoic acid )is a vitamin A analog that inhibits cell proliferation and induces cell differentiation. Clinically, 13-cis-Retinoic acid is primarily used in the treatment of severe recalcitrant nodular acne. Its effects include reducing the production of sebum, shrinking the size of the sebaceous glands, stabilizing keratinization, preventing comedones from forming, and reducing inflammation of inflammatory acne. Though the exact mechanism of action of 13-cis-Retinoic acid is not fully understood, studies have suggested that the compound alters DNA transcription and induces apoptosis in select types of cells throughout the body.
Function
It is a kind of raw material used in pharmaceutical area.
(1)It is a drug commonly used to treat acne vulgaris and keratosis pilaris.
(2)It is available as a cream or gel. It is also used to treat acute promyelocytic leukemia.
(3)It can stimulate skin growth and keep epidermic normal.
(4)It can slow down skin aging process for solarization, remove tiny wrinkles.
(5) It can reduce skin roughness, so skin will become ruddy.
Specification
Items | Specification | Results |
Description | Yellow crystalline powder | White crystalline powder |
Identification | Complies | Complies |
Organic Volatile Impurity | Complies | Complies |
Loss on drying | ≤0.5% | 0.18% |
residue on ignition | ≤0.1% | 0.05% |
Heavy Metals | ≤0.002% | 0.001% |
Limit of Tretinoin | ≤0.1% | 0.18% |
Assay | 98.0~102.0% | 99.4% |
CONCLUSION:CONFORM TO THE SPECIFICATION OF USP30. | ||

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Henan Kaixiang biological Technology Co., Ltd., was established in July 2017. It is a professional animal and plant extracts modern and advanced enterprise object, pharmaceutical intermediates, and natural active ingredients. In the development, production and marketing, is very powerful.
Headquartered in Henan. It has a research and development center and the Analysis and Testing Center, with strong comprehensive national strength. The company has 200 acres of experimental field of plant cultivation, extraction, distillation, rectification, chromatography, three specialized production lines, as well as 10,000 square meters of GMP standard workshop. A variety of production equipment more than 200 sets of experiments. US company to introduce the company WATERS LC-MS chromatograph and a 8453 UV-Vis spectrophotometerand Switzerland TLC scanner (HPTLC) and other advanced detection equipment to ensure the quality of our products are oriented to international standards Advanced equipment and professional and technical personnel, we are standing in front of the industry foundation, we thought to provide quality products and services to target customers around the word .
Kaixiang is the best choice of global customers .


1.We enjoy high reputation for years of sincerity business,have thousands of customers from all over the world.
2.We have advanced test equipments and production line of international standard to ensure the stability for our products quality.
3.Kaixiang Learning Organization has trained a group of professional staff,which are full of energy,ambitious,innovation.our outstanding team solve the technology and products as well as various of issues with their professional and passion.
4.Via the world wide internet,we can get many information of products demand and then to achieve the scale of supply.it also means which save the purchase cost and get mutual success.
5.Clients need our best concern,the rich experience of service for more than 32 countries and 3200 clients have guaranteed our products timely and safety arrive.
6.Reliable quality and excellent service is our commitment to every customers.we firmly believe our customer’s success is our success.at Kaixiang, we are always committed to giving our customers the reliable products and services that they expect and deserve.

1.Any inquiries will be replied with in 12 hours.
2.Dedication to quatity,supply& service.
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4.Reasonable & competitive price ,fast lead time.
5.Smple order in stock and one week for bulk production.
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