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Product Name: Estradiol
CAS: 57-91-0
MF: C18H24O2
MW: 272.38
EINECS: 200-023-8
Chemical Properties White Solid
α-Estradiol ( Alpha-estradiol )is an endogenous ligand for estrogen receptors ERα (Ki = 0.2 nM) and ERβ (Ki = 1.2 nM). Studies indicate that α- Estradiol is a short acting estrogen which only forms complexes with estrogen ligand receptors for a short period of time. These studies suggest that α-estradiol is beneficial in studying the affects caused by the MAPK signaling cascade such as cell division, neuronal differentiation, and neuronal survival in the developing brain. Furthermore, α-estradiol inhibits the influx of calcium in human aortic smooth muscle cells.
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