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CAPE
Phenethyl caffeate
CAS 104594-70-9
MF C17H16O4
MW 284.31
Synonyms Caffeic Acid 2-Phenylethyl Ester;CAFFEIC ACID PHENETHYLESTER (CAPE);CAPE,PhenethylCaffeate;CAFFEIC ACID PHENETHYL ESTER(CAPE)(P);KAFFEESUREPHENYLETHYLESTER;CAFFEICACIDPHENYLETHERESTER;3-(3,4-Dihydroxyphenyl)-2-propenoic acid 2-phenylethyl ester;Cafestol Acid Phenethyl Ester
Caffeic acid phenethyl ester (CAPE)/Phenethyl Caffeate is a natural phenolic chemical compound. It is the ester of caffeic acid and phenethyl alcohol.
CAPE is found in a variety of plants. It is also a component of propolis from honeybee hives.
1. Caffeic acid phenethyl ester has been shown to inhibit carcinogenesis, although other experiments show possible carcinogenic effects. It is also known as an antioxidant in vitro and also in vivo.
2. Caffeic acid phenethyl ester also shows immunomodulatory and anti-inflammatory activity.
3. Caffeic acid phenethyl ester outperformed the other antioxidants, reducing aflatoxin production by more than 95 percent. The studies are the first to show that oxidative stress that would otherwise trigger or enhance.Aspergillus flavus aflatoxin production can be stymied by caffeic acid. This opens the door to using natural anti-fungicide methods by supplementing trees with antioxidants.
4. Caffeic acid phenethyl ester outperformed the other antioxidants, reducing aflatoxin production by more than 95 percent. The studies are the first to show that oxidative stress that would otherwise trigger or enhance. Aspergillus flavus aflatoxin production can be stymied by caffeic acid. This opens the door to using natural anti- fungicide methods by supplementing trees with antioxidants.
1.Anti-mitogenic,
2.Anti-carcinogenic,
3.Anti-inflammatory,
4.Anti-cancer,
5.Immunomodulatory properties.
6.A potent and specific inhibitor of the activation of nuclear transcription factor NF-KB. It is also exhibits inhibitory activity against HIV-1 integrase with IC50 of 7uM