Rat Transforming growth factor beta 1 TGF beta 1 Elisa Kit

      Transforming Growth Factor Beta 1, 2, and 3 (TGF-beta 1, TGF-beta 2, and TGF-beta 3) are highly pleiotropic cytokines that virtually all cell types secrete. TGF-beta molecules are proposed to act as cellular switches that regulate processes such as immune function, proliferation, and epithelial-mesenchymal transition. Targeted deletions of these genes in mice show that each TGF-beta isoform has some non-redundant functions: TGF-beta 1 is involved in hematopoiesis and endothelial differentiation; TGF-beta 2 affects development of cardiac, lung, craniofacial, limb, eye, ear, and urogenital systems; and TGF-beta 3 influences palatogenesis and pulmonary development. The full range of in vitro biological activities of TGF-beta 5 has not yet been explored. However, TGF-beta 1, TGF-beta 2, TGF-beta 3, and TGF-beta 5 have been found to be largely interchangeable in an inhibitory bioassay, and it is anticipated that TGF-beta 5 will show a spectrum of activities similar to the other TGF-beta family members. To date, the production of TGF-beta 5 has only been demonstrated in Xenopus.<br/>TGF-beta ligands are initially synthesized as precursor proteins that undergo proteolytic cleavage. The mature segments form active ligand dimers via a disulfide-rich core consisting of the characteristic 'cysteine knot'. TGF-beta signaling begins with binding to a complex of the accessory receptor betaglycan (also known as TGF-beta RIII) and a type II serine/threonine kinase receptor termed TGF-beta RII. This receptor then phosphorylates and activates a type I serine/threonine kinase receptor, either ALK-1 or TGF-beta RI (also called ALK-5). The activated type I receptor phosphorylates and activates Smad proteins that regulate transcription. Use of other signaling pathways that are Smad-independent allows for distinct actions observed in response to TGF-beta in different contexts.

1. Sample require: we can provide sample.

    More details, welcome your contacting.

2. Quick delivery, usually within 1 to 3 days after your payment, within 10 days with mass quantity.

3. Fast and safe Shipping methods, such as DHL, FEDEX, TNT, UPS, EMS.

4. Various and convenient payment methods available, such as T/T, Western Union.

5. We insist: Customer first. High quality guarantee with best service for each customers.

Founded in 2004, Beijing Solarbio Science & Technology Co., Ltd. is a national high-tech enterprise, committed to providing high quality products and services for our loyal customers. Our products and services are mainly applied in molecular biology, cell biology, immunology and biomedical fields.

Solarbio has 30,00 square meters of research and production center, 2400 square meters of storage base and equipped with advanced logistics system. After 17 years of technological accumulation, we established an independent platform for immunology research and development. The platform include peptide design and synthesis, recombinant protein, antibody production and purification, primary antibody customization and related labeling and detection services, ELISA kit customization and other immunological product developments. Our mainly immunology products are antibodies and ELISA kits.

Now we can supply more than 10,000 primary antibodies, 300 secondary antibodies. With annual production capacity of 2000 antibodies we can provide more superior antibodies for customers. Solarbio technical team have rich experience in peptide design and recombinant protein expression, which enhanced the reliability of the antibodies. Solarbio have exceed 800 ELISA kits, the kits have high stability, good specificity and reliable quality. The detection species mainly include human, rat, mouse, bovine, swine and monkey. Besides these, we keep releasing new products, such as Cell separation medium, Staining kit, Biochemical assay kit, Reference materials, Cell signaling compounds. Through strict quality control, all of Solarbio products could ensured the authenticity and preciseness of the customers' experimental results.

1.Q: How about your samples?

    A: Depends on your quantity.

2.Q: What is your delivery time?

    A: Within 7 days after payment.

3.Q: How about your payment methods?

    A: T/T, Western Union, Also the payment could via alibaba.

4.Q: Are your manufacture?

    A: Yeah, we are. Our company is located in Beijing. You are welcome to visit our company.

5.Q: Which shipping methods do you have?

    A: Shipping by International Express, such as DHL, FEDEX, TNT, UPS, EMS.

Tina Zhao

Serve for you with all sincerity.

Beijing Solarbio Science & Technology Co., Ltd.

Third Floor, 85A, Lian dong U valley, Tongzhou Dist. Beijing, China.

Biochemical reagents; Stain; Elisa Kit; Antibody; Molecular biology; Cell culture medium; PCR reagents;DNA/RNA extract;  Small Molecule/Inhibitor; Standard...