Deoxyribonuclease / DNase I CAS 9003 98 9 High active

Soluble in water, slightly soluble in 30% ethanol and acetone, the optimum pH value of 7.8. Addition of 5 mmol/L Ca2+ or diisopropylfluorophosphate (DFP) to the aqueous solution increases its stability. The inhibitors are EDTA and sodium dodecyl sulfate; the activator is a divalent metal ion, and the best effect is obtained by combining Mg2+ with Ca2+. The 1% aqueous solution had an absorption coefficient of 11.1 at 280 nm. The average chain length for restriction digestion is four nucleotides, and the enzymatic reaction: deoxyribonucleic acid dinucleotide-5'-phosphate + oligonucleotide-5'-phosphate.

Application of High active Deoxyribonuclease / DNase I CAS 9003-98-9

Used For biochemical research, it is often used as a peony in clinical practice. It can also be used locally for abscesses, hematomas and intrathecal injections to treat meningitis.