Raw Material calcium folinate CAS 1492 18 8 Leucovorin Calcium

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Product Overview

Description

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Identification

 

NameLeucovorin Calcium, calcium folinate, CAS 1492-18-8
Structure  
Other namecalcium folinate
LEUCOVORIN CALCIUM
Folinic acid calcium salt
Folinate-SF Calcium
Calcium leucovorin
Leucovorin calcium salt
Folinic acid (Calcium)
1492-18-8
Key wordsPharmaceutical, drug,API; used to decrease the toxic effects of methotrexate and pyrimethamine; used in combination with 5-fluorouracil to treat colorectal cancer;treat folate deficiency
CAS NO.1492-18-8
Molecular FormulaC20H21CaN7O7
Molecular Weight511.508 g/mol

  

Chemical and Physical Properties
AppearanceWhite to off-white(solid)
Quality standard USP

 

Application
Drug IndicationFolinic acid may protect against bone marrow suppression or gastrointestinal mucosa inflammation.
folinic acid is sometimes used to reduce the side effects of methotrexate in rheumatoid arthritis patients. This includes reductions in nausea, abdominal pain, abnormal liver blood tests, and mouth sores.
Folinic acid is also used in combination with the chemotherapy agent 5-fluorouracil in treating colon cancer.
Folinic acid may be prescribed in the treatment of toxoplasmosis retinitis, in combination with the folic acid antagonists pyrimethamine and sulfadiazine.
It has been investigated for use in Down syndrome.
Formulations/Preparationstaken by mouth, injection into a muscle, or injection into a vein.
Handling and storage
Safety and HazardsThe shanghai Research Institute of Chemical industry testing center identification conclusion :1 None hazard identification, 2 The substance is not subject to IATA DGR, 3 Non packing requirements.
Handling and storageKeep container tightly closed in a dry and well-ventilated place. Light sensitive.
Sample packageAluminium foil bag
Commercial packageFiber drum
UN Code Not classfied
HS Code2942000000
Shipping groupShipment at ambient temperature for no controlled and  no dangerous goods
Sales restrictionNO
OriginChina

 

Technical Support
Leucovorin Calcium STD Data sheetYes
Leucovorin Calcium MSDSYes
Leucovorin Calcium COAYes
Leucovorin Calcium Transport certificateYes

 

Supply ability
Monthly capacity100 kg
DMFYes
GMPYes

 

Related APIs

Related APIS

Fludarabine phosphate
Aprepitant
Capecitabine
Lenalidomide
Methotrexate
Enzalutamide

 

 

 

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0.1912 s.