Factory Supply 99% Raw Material Sildenafil Citrate powder CAS 171599 83 0

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Product Overview

Description

Factory Supply 99% Raw Material Sildenafil Citrate powder CAS 171599-83-0 

Item Name
Sildenafil Citrate
CAS NO.
171599-83-0
Molecular Formula
C22H30N6O4S
Function
Treat Erectile Dysfunction.
Apparence
White Powder
Storage Conditon
Hygroscopic, -20℃ Freezer, Under Inert Atmosphere
Purity
99%
Advantage
OEM;ODM
Certificate
GMP/ISO9001
Payment
Trade Assurance; L/C; T/T; Western Union

What is Sildenafil Citrate?

Sildenafil is a vasoactive agent used to treat erectile dysfunction and reduce symptoms in patients with pulmonary arterial hypertension (PAH). Sildenafil elevates levels of the second messenger, cGMP, by inhibiting its breakdown via phosphodiesterase type 5 (PDE5). PDE5 is found in particularly high concentrations in the corpus cavernosum, erectile tissue of the penis. It is also found in the retina and vascular endothelium. Increased cGMP results in vasodilation which facilitates generation and maintenance of an erection. The vasodilatory effects of sildenafil also help reduce symptoms of PAH.

Indications

For the treatment of erectile dysfunction and to relieve symptoms of pulmonary arterial hypertension (PAH).


Associated Conditons

Erectile Dysfunction (ED)
NYHA Functional Class II-III Pulmonary arterial hypertension


Targets

1. cGMP-specific 3',5'-cyclic phosphodiesterase

2. Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma

3. Retinal cone rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma


Enzymes

1. Cytochrome P450 3A4

2. Cytochrome P450 3A5

3. Cytochrome P450 3A7

4. Cytochrome P450 2C9

5. Cytochrome P450 2C19

6. Cytochrome P450 2D6

7. Cytochrome P450 

8. Cytochrome P450 2E1

                                                                                                                                                                                                                  > > > Click Here To Contact Us

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Packing & Delivery
Fast safe shipping
For Europe, the United States, Russia, Australia, the Philippines, Thailand and other countries, we have special line transportation, we will help you complete the customs clearance, you just have to wait for the receipt of the package, this is a safe way of transportation.
By Special line transportation
By Express(DHL/FedEx)
By HK Postal/EMS
Successfully passed customs
Speedy delivery
Safer transportation
9-12 days
3-7 days
10-15 days
Door to door service
Door to door service
Door to door service
Customized Package Is Available.

We will always do our best to utilize the quickest and most affordable way for customers to receive orders.
And follow up with customers via email for all shipment details as well as updated track information until it arrives without damage.             
                                                                                                                  > > > Send Inquiry
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About us
Shanghai HuiRui Chemical Technology Co., Ltd.(HuiCHem) is a high-tech enterprise engaged in the area of health care & nutrition. HuiChem have been working closely with our customers we deliver products and solutions that create value and competitive advantage while positively impacting the world we live in, as well as attentive service for the purpose to meet the demand of customers, spare no effort to create value for customers.
HuiChem is now headquartered in Shanghai, and has offices in Jiangsu, Shandong, Anhui and HongKong. Its Shanghai headquarters has nearly 2000 square meters of operation premises, including a total of over 1500 square meters of synthesis laboratories and more than 200 square meters of analysis laboratories (equipped with AAS, LC-MS, FTIR, NMR and other basic test equipment). We have set up two pilot scale laboratories, which lay speedy and stable foundation for process amplification and production of superior products. Besides, we have partner factories that are responsible for the commercial production in Jiangsu Province and Shandong Province. All of those, ensuring growing customer demand and smooth commercial production. We have been certified ISO9001:2008 and ISO14001:2004. The company has established good cooperative relationships with Shanghai Institute of Organic Chemistry of Chinese Academy of Sciences(SIOC), Shanghai Institute of Materia Medica (SIMM), University of Science and Technology of China and Fudan University, and carried out a variety of creative R&D cooperation activities. 
FAQ
Q1. How does your factory control quality?
All the raw material purchasing and production quality control are strictly following the ISO9001: 2008 management system. Besides, the full-featured detection equipment and GMP quality management system to provide the strongest guarantee for high quality product. We can provide our customers the detailed test report for the quality evaluation before the sample.

Q2. What's your main markets? 
North America, Europe, Asia, etc.

Q3. What is your delivery term and delivery period? 
We accept FOB, CIF, etc. You can choose the one which is the most convenient or cost effective for you. The sample within 3 days, and bulk order within 5 days.

Q4. What is your package?
Powder: PE bag, glass bottle or PTFE bottle for inner packing, and aluminium foil bag for outer packing.
Liquid: glass bottle or PTFE bottle for inner packing, and aluminium foil bag for outer packing.
Bulk order: Fiber drum or steel drum.

Q5. What is the payment term? 
Normally we advise customers use Trade Assurance(is a free payment protection service for buyers is offered by Alibaba group), and we also receive T/T, Western Union or L/C.

Q6. Will you supply samples for test the quality? 
We'd like to offer our customers the free samples for the quality evaluation for most products, but the shipping cost is borne by customers.

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