Raw Material API Powder Tofacitinib citrate CAS 540737-29-9
In Stock USA warehouse supply raw Material API Powder Tofacitinib citrate CAS 540737-29-9 global fast delivery
Product Introduction:
Tofacitinib (formerly tasocitinib, CP-690550) is a drug being investigated by Pfizer for the treatment of rheumatoid arthritis (RA), psoriasis, inflammatory bowel disease, and other immunological diseases, as well as for the prevention of organ transplant rejection. It is an inhibitor of the enzyme Janus kinase 3 (JAK3), which means that it interferes with the JAK-STAT signaling pathway that transmits information outside the cell into the cell nucleus, influencing DNA transcription. Recently it has been shown in a murine model of established arthritis, tofacitinib rapidly improved disease by inhibiting the production of inflammatory mediators and suppressing STAT1-dependent genes in joint tissue. This efficacy in this disease model correlated with the inhibition of both JAK1 and 3 signaling pathways, suggesting that tofacitinib may exert therapeutic benefit via pathways that are not exclusive to inhibition of JAK3.
Specifciation:
Product Name: Tofacitinib Citrate
CAS No.: 540737-29-9
MF: C16H20N6O.C6H8O7
Appearance: White Powder
Purity: 98% min
Uses: Kinase inhibitors to treat rheumatoid arthritis.Raw material.
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Packaging & Shipping
1) 1kg/bag (1kg net weight, 1.1kg gross weight, packed in an aluminum foil bag) 2) 5kg/carton(1kg net weight, 1.1kg gross weight, packed in five aluminum foil bag)
3) 25kg/drum (25kg net weight, 28kg gross weight; packed in a cardboard-drum with two plastic-bags inside;
Drum Size: 510mm high, 360mm diameter)
Shipping:
1. Door to Door Service by DHL/FEDEX/EMS/TNT for package under 45kgs, about 3~7 days delivery.
2. Port to Port Service by Air for package more than 45kgs, about 3~7 days delivery.
3. Port to Port Service by Sea for package more than 500kgs, about 7~45 days delivery.
Company Information
Wuhan W&Z Biotech Co,.Ltd is a high-tech enterprise which focus on the R&D, production, sales and service of biomedical and large health field. It has strong scientific research strength, modern management system and high-quality marketing team.
W&Z, located in Wuhan, the national key science and education base, cooperates with Wuhan University, Huazhong University of Science and Technology and other well-known universities, forming a good R&D and production team. in our R & D team, there are five experts in fields.
W&Z focus on provide CRO and CMO services for customers on one-stop intermediates, APIs and green technology. We have established modern R&d laboratories in Wuhan Optical Valley, have two partner factories in Shandong and Sichuan. Besides supplying standard products with mature technology, we also do customize under customer`s personalized needs.
We will uphold the quality first, service-oriented, integrity-based purpose, committed to provide more and more, better and better services to the global customers.
