High Quality Recombinant Human SP D/Pulmonary surfactant associated protein D
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- Supplier: Beijing Solarbio Science & Technology Co. Ltd.
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Product Overview
Description
Recombinant Human SP-D/Pulmonary surfactant-associated protein D
Product Description
Product Information
| Description: | Recombinant Human Pulmonary Surfactant-Associated Protein D is produced by our Mammalian expression system and the target gene encoding Ala21-Phe375(Glu22Gly)? is expressed with a 6His tag at the C-terminus. |
|---|---|
| Synonym: | Pulmonary Surfactant-Associated Protein D; PSP-D; SP-D; Collectin-7; Lung Surfactant Protein D; SFTPD; COLEC7; PSPD; SFTP4 |
| Formulation: | Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.2. |
| Purity: | Greater than 95% as determined by reducing SDS-PAGE. |
| Endotoxin: | Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test. |
| Reconstitution: | Always centrifuge tubes before opening. Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100 μg/ml. Dissolve the lyophilized protein in ddH2O. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. |
| Storage: | Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months. |
Background
Surfactant Pulmonary-Associated Protein D (SP-D) is a 43 kDa member of the collectin family of innate immune modulators. Its principal components consist of a collagen-like region and a C-terminal carbohydrate recognition domain (CRD), a structure that places it in a subset of pattern recognition proteins termed defense collagens. SP-D is constitutively secreted by alveolar lining cells and epithelium associated with tubular structures and induced in cardiac smooth muscle and endothelial cells. It binds both secreted and transmembrane proteins that transduce its function. It binds human neutrophil defensins, modulating influenza anti-viral defense. It binds MD-2/LY96, a secreted protein that cooperates with Toll-like receptors (TLRs) in the response of macrophages to bacterial lipopolysaccharides (LPS) or cell wall components. It also binds macrophage CD14 and TLRs directly, blocking binding of LPS and down-regulating TNF-α secretion. SP-D binding of both SIRPα and the calreticulin/CD91 complex on macrophages allows for a graded response to environmental challenge.
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Company Information
Founded in 20 04, Beijing Solarbio Science & Technology Co., Ltd. is a national high-tech enterprise, committed to providing stable quality products and services for our loyal customers. Our products and services are mainly applied in molecular biology, cell biology, immunology and biomedical fields. Solarbio has 3, 000 sq.m of research and production center, 2, 4 00 sq.m of storage base and equipped with advanced logistics system. After 17 years of technological accumulation, we established an independent platform for immunology research and development. The platform include peptide design and synthesis, recombinant protein, antibody production and purification, primary antibody customization and related labeling and detection services, ELISA kit customization and other immunological product developments. Our mainly immunology products are antibodies and ELISA kits. Now we can supply more than 10, 000 primary antibodies, 300 secondary antibodies. With annual production capacity of 2, 000 antibodies we can provide more superior antibodies for customers. Solarbio technical team have rich experience in peptide design and recombinant protein expression, which enhanced the reliability of the antibodies. Solarbio have exceed 800 ELISA kits, the kits have high stability, good specificity and reliable quality. The detection species mainly include human, rat, mouse, bovine, swine and monkey. Besides these, we keep releasing new products, such as Cell separation medium, Staining kit, Biochemical assay kit, Reference materials, Cell signaling compounds. Through strict quality control, all of Solarbio products could ensured the authenticity and preciseness of the customers’ experimental results.
Our Services
1. Sample require: we can provide sample.
More details, Contact me by the following please.
Name: Amber Wong
Whats app: +8617611438982
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2. Quick delivery, usually within 1 to 3 days after your payment, within 10 days with mass quantity.
3. Fast and safe Shipping methods, such as DHL, FEDEX, TNT, UPS, EMS.
4. Various and convenient payment methods available, such as T/T, Western Union.
5. We insist: Customer first, high quality, best service for each customers.
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