Glycoprotein is a kind of compound glycoprotein which is composed of oligosaccharide chain and polypeptide chain.In glycoprotein, the composition of sugar is often more complex, mannose sugar, galactose, fucose, glucosamine, galactosamine, sialic acid. Oligosaccharides and proteins can be combined in two ways : the semi-acetal hydroxyl of sugar and the amino acids containing hydroxyl (serine, threonine, hydroxyl lysine, etc.) are bonded by o-glycoside bond;the hemiacetal hydroxyl of the sugar and the amide group of asparagine are bonded by n-glucoside bond.It is widely distributed in nature.Most of the 60 or 70 plasma proteins studied are glycoproteins.Some enzymes and hormones are glycoproteins.Glycoproteins are also important components of plasma membrane, intercellular and plasma mucus.More and more glycoproteins are isolated from plants, especially lectin.Many lectins have been isolated from vertebrates and invertebrates, and even from many microorganisms, most of which are glycoproteins.Glycoproteins are species-specific. One protein is present in the form of glycoproteins in one animal and not in another.Even if they are glycoproteins, their sugar content may be different. For example, the trypsin of cattle, sheep and pigs are all glycoproteins, but their sugar content is 9.4%, 9.8% and 38%, respectively.The rats had no sugar.
Glycoprotein is also a binding protein. Glycoproteins are molecules composed of short oligosaccharide chains covalently linked to proteins, and their overall properties are more similar to those of proteins.
Product Details of glycoprotein
Glycoproteins are proteins containing sugar, which are covalently linked by glycoside bonds between oligosaccharide chains and certain amino acid residues in peptide chains. The formation of glycoproteins in cells The formation of glycoproteins in cells Its main biological function is the biometrization of cell or molecule. For example, sperm needs to recognize the corresponding glycoprotein on the cell membrane of egg when egg is fertilized.Receptor proteins and tumor cell surface antigens are also glycoproteins.Glycoproteins are widely found in animals, plants and microorganisms.It can be divided into three categories according to the mode of existence:
Product Details of glycoprotein
1. Soluble glycoprotein, which is found in intracellular fluid, various body fluids and mucus secreted by lumen glands.All plasma proteins except albumin are glycoproteins.Soluble glycoproteins include enzymes (such as nuclease, protease and glycosidase), peptide hormones (such as chorionic gonadotropin, luteinizing hormone, thyrotropin and erythropoietin), antibodies, complement, as well as certain growth factors, interferons, statins, lectin and toxins. 2. Membrane bound glycoprotein, whose peptide chain is composed of hydrophobic peptide and hydrophilic peptide.Hydrophobic peptides can be one or more and are embedded in the membrane lipid layer by hydrophobic interaction.The hydrophilic peptide segment is exposed to the membrane.Sugar chains are attached to hydrophilic peptides and have strict directivity.On the surface of plasma membrane, the sugar chain faces outwards.The inner membrane of cells generally faces the lumen.usually refers to a polymer consisting of 2 ~ 10 monosaccharide groups bonded by glycoside.The oligosaccharide chain of glycoproteins is often branched.The diversity of sugar chain structures exceeds that of polynucleotides and peptides, as monosaccharides have alpha and beta terminal carbon (heterocephalic carbon) atoms and multiple hydroxyl groups that form glycoside bonds in monosaccharide molecules.It can store enough recognition information in the structure of sugar chain and play a decisive role in molecular recognition and cell recognition.The physiological functions of glycoproteins include coagulation, immunity, secretion, endocytosis, material transport, information transmission, nerve conduction, regulation of growth and differentiation, cell migration, cell homing, wound repair and regeneration, etc.The sugar chain of glycoprotein is also involved in maintaining its peptide chain in a biologically active natural conformation and stabilizing the peptide chain structure, and endowing the whole glycoprotein molecule with specific physicochemical properties (such as lubricity, viscoelasticity, heat inactivation resistance, protease hydrolysis resistance and frost resistance, etc.).
Product Details of glycoprotein
Glycoproteins are associated with many diseases such as infection, cancer, cardiovascular disease, liver disease, kidney disease, diabetes, and some glycoprotein glycoprotein The occurrence and development of hereditary diseases.Furthermore, glycoproteins and lipids on the cell surface can be "shed" into the surrounding environment or blood circulation, which can be used as markers of abnormalities to provide information for clinical diagnosis.Specific or weak changes in glycoproteins in body fluids during certain diseases may be helpful in diagnosis or prognosis.Glycoproteins are also increasingly involved.For example, antibodies that target specific sugar structures on specific cell surfaces may serve as targeted vectors for therapeutic drugs.The use of sugars (monosaccharides, oligosaccharides or glycopeptides) to fight infection and tumor metastasis has also emerged.
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FAQ
Q1: Do you accept Alibaba Trade Assurance?
A: Yes, most of our products accept Alibaba Trade Assurance.
Q2. Can I have free samples?
A:Yes, we can supply the free sample for 10-20g except high value products, but the shipping cost need you to pay. Sample shipping fee Generally for 45$ .
Q3. How do I pay the sample fee?
A: Paypal,Western Union,T/T or just provide your courier's account number, we prefer FEDEX.
Q4. How do you treat quality complaint?
A: For us, quality is our second life. The quality control of all the products we export is very strict. All the products we promise to provide to our customers are completely higher than the national food safety standards. It is our duty to control the quality of the goods. Please rest assured!
Anyway If any qulitity problem caused by our company after Third Party Test , You can return goods back to us and we refund your payment.But this problem will never happened because of our high qulitity.Please rest assured.
Q5. What's your MOQ and lead time?
A: Generally MOQ is 1kg, some low value products, MOQ is 25kg and lead time is within 4-5 workdays upon your payment.
Q6. Which products you can export?
A: We are mainly exporting herbal extracts, amino acids, vitamins, cosmetics and APIs.
Q7: Which countries or region did you export?
A: US,Canada, India, Thailand ,Vietnam.Taiwan region, Japan, Poland, Spain, France, UK, Germany, Italy, Bulgaria, Greece, Hungary, Australia, Iceland, Qata, Mexico, Brazil,South Korea,Kuweit,Turkey,Russia,Austria,Nigeria,Guatemala,Iran,Sweden,Phhilippines,Iraq, Pakistan, South Africa,Denmark,Kenya and so on
Q8:Which documents you can provide?
A:Usually, we provide Commercial Invoice, Packing List, Bill of loading, COA , Health certificate and Origin certificate.
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