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CAS 99291-24-4 Levodropropizine


Levodropropizine is a cough suppressant. It is the levo isomer of dropropizine. It acts as a peripheral antitussive, with no action in the central nervous system. It does not cause side effects such as constipation or respiratory depression which can be produced by antitussives.

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Specifications |
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Description |
white or almost white powder |
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Solubility |
Slightly soluble in water and in ethanol(96),freely soluble in dilute acetic acid and in methanol, |
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Identification |
A: Specific rotation:-30.0°~-33.5° |
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B: By IR, To match with working standard |
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PH |
9.2~10.2 |
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Impurity B |
No more than 0.5% |
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Related Substances |
Each impurity no more than 0.1% Total impurities≤0.6% |
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Impurity C |
No more than 10ppm |
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Enantiomeric purity |
Impurity A no more than 2.0% |
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Loss on drying |
≤1.0% |
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Sulfated ash |
≤0.2% |
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Residual solvent |
Acetone ≤0.5% |
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Dichloromethane ≤0.06% |
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Assay |
98.5%~101.0% |
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Conclusion |
Conform with specification |
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Storage |
Store in sealed containers at cool & dry place. Protect from light, moisture and pest infestation. |
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Shelf life |
2 years when properly stored |





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