CAS 99291 24 4 Levodropropizine

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Product Overview

Description

CAS 99291-24-4 Levodropropizine

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Levodropropizine is a cough suppressant. It is the levo isomer of dropropizine. It acts as a peripheral antitussive, with no action in the central nervous system. It does not cause side effects such as constipation or respiratory depression which can be produced by  antitussives.

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Tests

Specifications 

Description

white or almost white powder

Solubility

Slightly soluble in water and in ethanol(96),freely soluble in dilute acetic acid and in methanol,

 

 

Identification

A: Specific rotation:-30.0°~-33.5°

B: By IR, To match with working standard

PH

9.2~10.2

Impurity B

No more than 0.5%

Related Substances

Each impurity no more than 0.1%

Total impurities≤0.6%

Impurity C

No more than 10ppm

Enantiomeric purity

Impurity A no more than 2.0%

Loss on drying

≤1.0%

Sulfated ash

≤0.2%

Residual solvent

                Acetone ≤0.5%

Dichloromethane ≤0.06%

Assay

98.5%~101.0%

Conclusion 

Conform with specification

 

Storage

Store in sealed containers at cool & dry place.

Protect from light, moisture and pest infestation.

Shelf life 

2 years when properly stored

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0.1891 s.