Chlorhexidine is an odorless, white crystalline powder, odorless, bitter taste, hardly soluble in water or alcohol. Chlorhexidine, Chlorhexidine Dihydrochloride, Chlorhexidine Digluconate and Chlorhexidine Diacetate are used as cosmetic biocides, oral care agents and preservatives. It is a disinfect and antiseptic medicine, strong function of broad-spectrum bacteriostasis, sterilization, used for disinfecting hands, medical apparatus and instruments, wound ,skin and so on.
Function:
1) In cosmetics and personal care products, Chlorhexidine and its salts (Chlorohexidine Dihydrochloride, Chlorhexidine Digluconate, Chlorhexidine Diacetate) are used in the formulation of eye makeup, makeup foundations, mouthwashes, hair dyes and bleaches,and other skin care and hair care products; 2) Chlorhexidine has been used in medical practice and these ingredients, particularlythe Digluconate salt, have extensive use in dentistry because they inhibit plaque formation; 3) Chlorhexidine is used as a topical antiseptic skin scrub in hospital and household settings; 4) For use in animals, it is used as a topical disinfectant of wounds.
Application:
Chlorhexidine salts are widely used in pharmaceutical formulations in Europe and Japan for their antimicrobial properties.Although mainly used as disinfectants, chlorhexidine salts are also used as antimicrobial preservatives. As excipients, chlorhexidine salts are mainly used for the preservation of eye-drops at a concentration of 0.01% w/v; generally the acetate or gluconate salt is used for this purpose. Solutions containing 0.002–0.006% w/v chlorhexidine gluconate have also been used for the disinfection of hydrophilic contact lenses. For skin disinfection, chlorhexidine has been formulated as a 0.5% w/v solution in 70% v/v ethanol and, in conjunction with detergents, as a 4% w/v surgical scrub. Chlorhexidine salts may also be used in topical antiseptic creams, mouthwashes, dental gels, and in urology for catheter sterilization and bladder irrigation.Chlorhexidine salts have additionally been used as constituents of medicated dressings, dusting powders, sprays, and creams.
