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Ciprofloxacin hcl Quick details
Ciprofloxacin is used to treat or prevent certain infections caused by bacteria.Ciprofloxacin is also used to treator prevent anthrax in people who may have been exposed to anthrax grems in the air.Ciprofloxacin is in a classof antibiotics called fluoroquinolones.It works by killing bacteria that cause infections.

Ciprofloxacin hcl Function
Antibiotics will not workfor colds,flu,or other viral infections.
Ciprofloxacin is used to treat a wide variety of infections, including infections of bones and joints, endocarditis,gastroenteritis, malignant otitis externa, respiratory tract infections, cellulitis, urinary tract infections,prostatitis, anthrax, and chancroid.
Ciprofloxacin only treats bacterial infections; it does not treat viral infections such as the common cold. For certain uses including acute sinusitis, lower respiratory tract infections and uncomplicated gonorrhea, ciprofloxacin is not considered a first-line agent.
Ciprofloxacin occupies an important role in treatment guidelines issued by major medical societies for the treatment of serious infections, especially those likely to be caused by Gram-negative bacteria, including Pseudomonas aeruginosa.
Ciprofloxacin hcl Application
1. Ciprofloxacin HCl drug is used for the treatment of Bacterial infection of Respiratory tract, UTI, Uncomplicated Cystitis in females, GI, Chronic Bacterial Prostatitis, CNS, Immuno compromised patients, Skin, Bone and Joint Infections, Uncomplicated cervical and urethral gonorrhea.
2. Ciprofloxacin HCl drug has in vitro activity against a wide range of gram-negative and gram-positive organisms.
3.Ciprofloxacin HCl drug inhibits bacterial DNA gyrase, an enzyme responsible for counteracting excessive supercoiling of DNA during replication or transcription. The mechanism of action of quinolones, including Ciprofloxacin HCl drug, is different from that of other antimicrobial agents such as betalactams, macrolides, tetracyclines, or aminoglycosides; therefore, organisms resistant to these drugs may be susceptible to Ciprofloxacin HCl drug. There is no known crossresistance between ciprofloxacin HCl drug and other classes of antimicrobials.
Ciprofloxacin hcl Specification
ITEMS | SPECIFICATION | RESULT |
Identification | IR conforms to the USP ciprofloxacin RS spectrum | Conforms |
TLC: the intensity and Rf value of the principal band obtained from the test solution corresponds to that obtained from the standard solution | ||
Clarity of solution | (0.25g/10ml 0.1M HCL) | Conforms |
Loss on drying | 1.0% | 0.5% |
Residue on ignition | NMT 0.1% | 0.2% |
Chloride | NMT 0.02% | Conforms |
Sulfate | NMT 0.04% | Conforms |
Heavy metals | NMT 20 PPM | <20 PPM |
Fluoroquinolonic acid | NMT 0.2% | <0.2% |
Related substance | Ciprofloxacin ethylenediamine analos NMT0.2% | 0.04% |
Any other single impurity NMT 0.2% | 0.02% | |
Total impurities NMT 0.5% | 0.45% | |
Assay(on the anhydrous basis) | 98.0%-102.0% | 99.7% |







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