Tadafilo vitamins sidenafil oral thin film making machine
- Category: >>>
- Supplier: ZHEJIANG LEADTOP PHARMACEUTICAL MACHINERY CO. LTD
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Product Overview
Description
OralTop-300 Oral Thin Film Coating Machine
Brief Introduction:
OralTop-Series Oral Thin Film making machine is specially designed and manufactured for making medicine film on paper, plastic film, metal film,etc. The active ingredient can be either dissolved or suspended in the polymeric matrix. OralTop-Series is used for making roll type Oral Thin Film.
Oral Thin Films with systemic activity for rapid delivery. An Oral Thin Film (OTF) is a very thin film, composed of a mono or multi-layer polymeric matrix, which is applied in the mouth. OTF are often water based soluble polymers designed to rapidly deliver drugs systematically. Depending on the drug candidate and the targeted indication, OTF can be formulated either as:
1. Orodispersible films working like conventional orodispersible products. In this case OTF dissolves within seconds in the mouth and the drug substance is swallowed together with the saliva.
Oral Thin Films with systemic activity for rapid delivery. An Oral Thin Film (OTF) is a very thin film, composed of a mono or multi-layer polymeric matrix, which is applied in the mouth. OTF are often water based soluble polymers designed to rapidly deliver drugs systematically. Depending on the drug candidate and the targeted indication, OTF can be formulated either as:
1. Orodispersible films working like conventional orodispersible products. In this case OTF dissolves within seconds in the mouth and the drug substance is swallowed together with the saliva.
2. Or as a transmucosal film, where the active substance directly enters the systemic circulation via the buccal mucosa, avoiding the hepatic first pass effect.
The OTF dosage form presents several advantages, among which:
1. An easy drug intake therefore high acceptance by young and old patient thanks no swallowing difficulties and no beverages requirement for intake.
2. Flexible manufacturing with area proportional dosage (different doses from one base bulk).
3. Potential avoidance of the first-pass effect and improved bioavailability.
4. Innovative and appealing design offering more options for differentiating a product range.
The OTF dosage form presents several advantages, among which:
1. An easy drug intake therefore high acceptance by young and old patient thanks no swallowing difficulties and no beverages requirement for intake.
2. Flexible manufacturing with area proportional dosage (different doses from one base bulk).
3. Potential avoidance of the first-pass effect and improved bioavailability.
4. Innovative and appealing design offering more options for differentiating a product range.
Main Feature:
1. Coating thickness from 40 – 1000 microns wet.
2. High coating accuracy.
3. Individual temperature adjustment zones.
4. Recording of all process related parameters.
5. Variable speed of base film.
6. Uniform air flow throughout the machine.
7. cGMP Construction.
8. Liquid dosing system with peristaltic pump.
9. Thickness checking or wet & dry film.
2. High coating accuracy.
3. Individual temperature adjustment zones.
4. Recording of all process related parameters.
5. Variable speed of base film.
6. Uniform air flow throughout the machine.
7. cGMP Construction.
8. Liquid dosing system with peristaltic pump.
9. Thickness checking or wet & dry film.
Options:
1. Products temperatures & film temperature measurement.
2. Recording of critical process data in 21 CFR part 11 certified software.
3. Report on excel file can be exported to USB to view on computer.
4. Equipment can be modified to make patch film of desired size and desired web length.
5. Cutting and Sitting line are a part of the complete processing line for oral strips.
6. Cutting line for cutting into small uniform strips & individual strip packing line.
7. Customer required designs and style / colors for printing.
8. Homogenizers and mixing tanks for integrations for a complete MDF suite.
9. Special style / shape for packing each film / multiple films.
2. Recording of critical process data in 21 CFR part 11 certified software.
3. Report on excel file can be exported to USB to view on computer.
4. Equipment can be modified to make patch film of desired size and desired web length.
5. Cutting and Sitting line are a part of the complete processing line for oral strips.
6. Cutting line for cutting into small uniform strips & individual strip packing line.
7. Customer required designs and style / colors for printing.
8. Homogenizers and mixing tanks for integrations for a complete MDF suite.
9. Special style / shape for packing each film / multiple films.
Main Technical Data:
Item | Specification |
Model | OralTop-300 |
Max.Production Width | 300mm |
Max. Line Speed | 10m/min (depend on medicine) |
Drying/Heating Method | Stainless Steel Heat Exchanger |
Temperature Range | 20-150℃ |
Total Power | 18kw |
Power Supply | 380v 50hz three phase or 220v 50hz three phase |
Overall Dimension | 2700*1200*2300mm |
Product Contact Parts Material | SS316L |
Control System | PLC and Touch Screen control |
Machine Frame Material | SUS304 |
Final Products:
Q: What price terms you offer?
A: We can offer FOB, FCA, CFR, CIF, EXW and other price terms based on your request.
Q: What payment terms you take?
A: TT, LC, other terms are also workable.
Q: Will you help with installation and stuff training?
A: Yes, we can send our engineers to your place to guide the installation and train your workers if you need, but the buyer should
bear our technician's round tickets, accomodation, food and subsidiary USD100/day.
Q: How can I visit your factory?
A: Our factory is located in Ruian city Zhejiang Province. Just let us know your scheduel in advance and we will arrange
everything for you!
Any other doubts about our machine, please feel easy to contact with us.
A: We can offer FOB, FCA, CFR, CIF, EXW and other price terms based on your request.
Q: What payment terms you take?
A: TT, LC, other terms are also workable.
Q: Will you help with installation and stuff training?
A: Yes, we can send our engineers to your place to guide the installation and train your workers if you need, but the buyer should
bear our technician's round tickets, accomodation, food and subsidiary USD100/day.
Q: How can I visit your factory?
A: Our factory is located in Ruian city Zhejiang Province. Just let us know your scheduel in advance and we will arrange
everything for you!
Any other doubts about our machine, please feel easy to contact with us.
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