Fungicide mixture Dimethomorph 9% Mancozeb 60% WDG agrochemical

Active ingredient

Dimethomorph 9% + Mancozeb 60% WDG 

Classification

Fungicide / Agrochemical

Biochemistry

Dimethomorph : Inhibits the formation of the oomycete fungal cell wall.

Mancozeb: Reacts with, and inactivates the sulfhydryl groups of amino acids and enzymes of fungal cells, resulting in disruption of lipid metabolism, respiration and production of ATP.

 Mode of action

Dimethomorph : Local systemic fungicide with good protectant and antisporulant activity. Only the (Z)- isomer is intrinsically active, but, because of rapid interconversion of isomers in the light, it has no advantage over the (E)- isomer in practice.

Mancozeb: Fungicide with protective action.  

Usage

   Dimethomorph:  Fungicide effective against Oomycetes, especially Peronosporaceae and Phytophthora spp. (but not Pythium spp.) in vines, potatoes, tomatoes and other crops. Used in combination with contact fungicides, and applied at 2.0-2.5 kg formulated product/ha.

   Mancozeb: Control of many fungal diseases in a wide range of field crops, fruit, nuts, vegetables, ornamentals, etc. More frequent uses include control of early and late blights (Phytophthora infestans and Alternaria solani) of potatoes and tomatoes; downy mildew (Plasmopara viticola) and black rot (Guignardia bidwellii) of vines; downy mildew (Pseudoperonospora cubensis) of cucurbits; scab (Venturia inaequalis) of apple; sigatoka (Mycosphaerella spp.) of banana and melanose (Diaporthe citri) of citrus. Typical application rates are 1500-2000 g/ha. Used for foliar application or as a seed treatment.

Mammalian Toxicology

  Dimethomorph:  ral Acute oral LD50 for rats >5000 mg/kg.  Skin and eye Acute percutaneous LD50 for rats >10 000, rabbits >5000 mg/kg. No irritation to skin (rabbits); moderate eye irritant (rabbit, EU standards), not an eye irritant (rabbit, U.S. standards) No dermal sensitisation in Buehler test; may cause dermal sensitisation in guinea pig maximisation test.  Inhalation LC50 (4 h) for rats >5.14 mg/l. 

  Mancozeb:   Oral Acute oral LD50 for rats >5000 mg/kg.  Skin and eye Acute percutaneous LD50 for rats >10 000, rabbits >5000 mg/kg. No irritation to skin (rabbits); moderate eye irritant (rabbit, EU standards), not an eye irritant (rabbit, U.S. standards) No dermal sensitisation in Buehler test; may cause dermal sensitisation in guinea pig maximisation test.  Inhalation LC50 (4 h) for rats >5.14 mg/l. 

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