Veterinary product Milbemycin oxime cas no.129496 10 2

Tests

Specifications

Test results

Description 

White to slightly yellow powder,hygroscopic

White 

powder

Identification

IR: IR spectrum of the sample corresponds to 

that of the mibemycin oxime RS

Conforms

HPLC:The retention time of the major peaks 

of the sample solution corresponds to that of 

the standard solution, as obtained in the assay.

Conforms

Water  

             ≤2.0%

1.3%

Related compounds

11-desmethyl milbemycin A4 oxime: ≤0.7%

0.06%

Milbemycin D-oxime:≤ 3.0%

0.47%

Any other individual impurity: ≤ 0.5%

0.36%

Total impurities: ≤ 5.0%

1.95%

Assay (HPLC)

Sum of milbemycin A4 oxime and milbemycin 

A3 oxime:

 95.0%~101.0%(on the anhydrous basis)

98.7%

The ratio of milbemycin A4 oxime: ≥ 80%

87.0%

The ratio of milbemycin A3 oxime: ≤ 20%

11.7%

Conclusion: The Product complies with in-house standard.